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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
32.12
Human Site:
Y152
Identified Species:
54.36
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
Y152
A
E
N
M
I
Q
T
Y
S
N
G
S
T
K
D
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
Y379
A
E
N
M
I
Q
T
Y
S
N
G
S
T
K
D
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
C244
A
E
N
M
T
H
T
C
A
S
G
T
P
K
E
Dog
Lupus familis
XP_542019
1076
118222
Y285
A
E
N
M
I
Q
T
Y
S
N
G
S
T
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
Y152
A
E
N
M
I
Q
T
Y
S
N
G
S
S
K
D
Rat
Rattus norvegicus
Q63433
946
104449
Y152
A
E
N
M
I
Q
T
Y
S
N
G
S
T
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Y231
A
E
N
M
I
Q
M
Y
A
N
G
T
P
K
E
Chicken
Gallus gallus
XP_422357
1013
114806
Y189
A
E
N
M
I
Q
M
Y
S
N
G
S
S
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
Y170
A
E
N
M
I
P
I
Y
T
N
G
S
T
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Q53
E
Y
H
I
G
K
T
Q
V
R
P
K
T
N
E
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
A105
A
Q
K
G
L
V
E
A
S
H
K
L
D
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
K142
E
A
N
T
K
L
T
K
L
Y
Q
I
D
G
D
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y187
I
E
K
M
V
Q
L
Y
Q
M
E
G
D
K
K
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
46.6
100
N.A.
93.3
100
N.A.
66.6
86.6
N.A.
80
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
86.6
N.A.
0
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
8
0
0
0
0
0
8
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
58
% D
% Glu:
15
72
0
0
0
0
8
0
0
0
8
0
0
0
22
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
65
8
0
8
0
% G
% His:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
8
58
0
8
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
15
0
8
8
0
8
0
0
8
8
0
72
8
% K
% Leu:
0
0
0
0
8
8
8
0
8
0
0
8
0
0
8
% L
% Met:
0
0
0
72
0
0
15
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
72
0
0
0
0
0
0
58
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
8
0
15
0
0
% P
% Gln:
0
8
0
0
0
58
0
8
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
50
8
0
50
15
0
0
% S
% Thr:
0
0
0
8
8
0
58
0
8
0
0
15
43
0
0
% T
% Val:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _